Reserch ProjectPublicationsトMembersActivities Report

Original Paper (2001~2010)

2010

147 Joni Prasetyo,Tatsuya Kato,and Enoch Y. Park, Efficient cellulase-catalyzed saccharification of untreated paper sludge targeting for biorefinery ,Biomass and Bioenergy., 34(12);1906-1913(2010)
146 Dwiarti Lies, Ali E, and Enoch Y. Park, Enhancement of lipase catalyzed-fatty acid methyl esters production from waste activated bleaching earth by nullification of lipase inhibitors., Bioresour Technol.101(1):14-20 (2010)
145 Xing-hua Li, Hua-junYang, Bhaskar Roy, Enoch Y. Park, Li-jun Jiang, Dan Wang, Yun-gen Miao, Enhanced cellulase production of the Trichoderma viride mutated by microwave and ultraviolet,Microbiol. Res., 165:190-198(2010)
144 Tatsuya Kato, Kengo Yoshizuka, Enoch Y. Park, New strategy for rapid isolation of stable cell lines from DNA-transformed insect cells using fluorescence activated cell-sorting, J. Biotechnol.147,102-107(2010)
143 Joni Prasetyo, Shyuuhei Sumita, Naoyuki Okuda, Enoch Y. Park, Response of cellulase activity in pH-controlled cultures on the filamentous fungus Aceremonium cellulolyticus, Appl. Microbiol. Biotechnol.,162:52-61(2010).
142 Tatsuya Kato, Mizuho Kajikawa, Katsumi Maenaka, Enoch Y. Park, Silkworm expression system as a platform technology in life science, Appl. Microbiol. Biotechnol.,85:459-470(2010).DOI:10.1002/btpr.313.
141 Takashi Sugimoto, Aki Morimoto, Masashi Nariyama, Tatsuya Kato, Y.Park, Isolation of an oxalate-resistant Ashbya gossypii strain and its improved riboflavin production, J. Ind. Micropbiol. Biotechnol., 37:57-64(2010),DOI 10.1007/s10295-009-0647-3.
140 Lies Dwiarti, Ehsan Ali , Enoch Y. Park, Enhancement of lipase catalyzed-fatty acid methyl esters production from waste activated bleaching earth by nullification of lipase inhibitors,Bioresource Technol.,101.14-20(2010).DOI:10.1016/j.biortech.2009.08.032
139 Takashi Dojima, Takuya Nishina, Tatsuya Kato, Tsuyoshi Uno, Hirokazu Yagi, Koichi Kato, Hiroshi Ueda, Enoch Y. Park, Improved secretion of molecular chaperone-assisted human IgG in silkworm, and no alterations in their N-linked glycan structures, Biotechnol. Prog.,26(1)232-238(2010).DOI:10.1002/btpr.313.

2009

138 Kaori Sasaki, Mizuho Kajikawa, Kimiko Kuroki, Tomoko Motohashi, Tsukasa Shimojima, Enoch Y Park, Sachiko Kondo, Hirokazu Yagi, Koichi Kato, Katsumi Maenaka, Silkworm expression and sugar profiling of human immune cell surface receptor, KIR2DL1, Biochem. Biophys. Res. Commun., 387(3),575-80(2009).
137 Mitsuyasu Okabe, Dwiarti Lies, Shin Kanamasa, Enoch Y. Park, Biotechnological production of itaconic acid and its biosynthesis in Aspergillus terreusAppl. Microbiol. Biotechnol.,84(4)597-606(2009).DOI:10.1007/s00253-009-2132-3.
136 Takashi Dojima, Takuya Nishina, Tatsuya Kato, Tsuyoshi Uno, Hirokazu Yagi, Koichi Kato and Enoch Y. Park,Comparison of the N-linked glycosylation of human beta1,3N-acetylglucosaminyltransferase 2 expressed in insect cells and silkworm larvae, J. Biotechnol., 143(1), 27-33 (2009).
135 Tatsuya Kato, Suganthi Lavender Manohar, Shigeyasu Tanaka, Enoch Y. Park, High-titer preparation of Bombyx mori nucleopolyhedrovirus (BmNPV) displaying recombinant protein in silkworm larvae by size exclusion chromatography and its characterization, BMC Biotechnol., 9: 55 pp1-11 (2009).
134 Makoto Ogata, Makoto Nakajima, Tatsuya Kato, Takikiyo Obara, Hirokazu Yagi, Koichi Kato, Taichi Usui and Enoch Y. Park, Synthesis of sialoglycopolypeptide for potentially blocking Influenza virus infection using a rat alpha2,6-sialyltransferase expressed in BmNPV bacmid-injected silkworm larvae, BMC Biotechnol., 9: 54, pp1-13 (2009).
133 Kajikawa, M, Sasaki K, Wakimoto Y, Toyooka M, Motohashi T, Shimojima S, Takeda S, Park EY, Maenaka K, Efficient silkworm expression of human GPCR (nociceptin receptor) by aBombyx mori bacmid DNA system, Biochem. Biophys. Res. Commun., 385, 375-379 (2009).
132

D. Du, T. Kato, F. Suzuki, Enoch Y. Park, Expression of protein complex comprising of the human prorenin and (pro)renin receptor in silkworm larvae using Bombyx mori nucleopolyhedrovirus (BmNPV) bacmids for improving biological function, Mol. Biotechnol., 43(2):154-161(2009).

131 S. Tajima, Y. Itoh, T. Sugimoto, T., Enoch Y. Park,> Increased riboflavin production from activated bleaching earth by a mutant strain of Ashbya gossypii,J. Biosci. Bioeng., 108(4),325-329(2009).
130 D. Du, T. Kato, F. Suzuki, Enoch Y. Park, Binding Affinity of full length and extracellular domains of recombinant human (Pro)renin receptor to human renin when expressed in the fat body and hemolymph of silkworm larvae, J. Biosci. Bioeng., 108(4);304-9 (2009).
129 M. Nakajima, T. Kato, S. Kanamasa, Enoch Y Park, Molecular chaperone-assisted production of human alpha-1,4-N-acetylglucosaminyltransferase in silkworm larvae using recombinant BmNPV bacmids, Mol. Biotechnol., 43(1);67-75 (2009).
128 T. Sugimoto, S. Kanamasa, T. Kato, Enoch Y. Park, Importance of malate synthase in the glyoxylate cycle of Ashbya gossypii for the efficient production of riboflavin, Appl. Microbiol. Biotechnol., 83(3):529-39 (2009).
127 M. Ogata, K.I.P.J. Hidari, W. Kozaki, T. Murata, J. Hiratake, Enoch Y. Park, T. Suzuki, T. Usui, Molecular design of spacer-N-linked sialoglycopolypeptide as polymeric inhibitors against influenza virus infection, Biomacromolecule, 10, 1894-1903 (2009).
126 T. Dojima, T. Nishina, T. Kato, H. Ueda, Enoch Y. Park, Comparison of the efficiencies of different affinity tags in the purification of a recombinant secretory protein expressed in silkworm larval hemolymph, Biotechnol. Bioproc. Eng., 14, 281-287 (2009).
125 M. Mori, E. Ali, D. Du, Enoch Y. Park, Characterization and optimization of extracellular lipase production by Alcaligenes sp. using stearic acid as carbon source, Biotechnol. Bioproc. Eng., 14, 193-201 (2009).
124 M. Ogata, K. Hidari, T. Murata, S. Shimada, W. Kozaki, Enoch Y. Park, T. Suzuki, T. Usui, Chemoenzymatic synthesis of sialoglycopolypeptides as glycomimetics to block infection by avian and human influenza viruses. Bioconjugate Chem., 20, 538-549 (2009).
123 Tatsuya Kato, Dongning Du, Fumiaki Suzuki, Enoch Y. Park, Localization of human (pro)renin receptor lacking the transmembrane domain on budded baculovirus of Autographa californica multiple nucleopolyhedrovirus, Appl. Microbiol. Biotechnol. 82, 431-437 (2009).
122 M. Ishikiriyama, T. Nishina, T. Kato, H. Ueda,Enoch Y. Park,Human single-chain antibody expression in the hemolymph and fat body of silkworm larvae and pupa using BmNPV bacmids, J. Biosci. Bioeng., 107, 67-72 (2009).
121 Enoch Y. Park, M. Ishikiriyama, T. Nishina, T. Kato, H. Yagi, K. Kato, H. Ueda, Human IgG expression in silkworm larval hemolymph using BmNPV bacmids and its N-linked glycan structure,J. Biotechnol., 39, 108-114 (2009).

2008

120 N. Kawakami, JM Lee, H. Mon, Y. Kubo, Y. Banno, Y. Kawaguchi, K. Maenaka, Enoch Y. Park, K. Koga, T. Kusakabe, Efficient protein expression in Bombyx mori larvae of the strain d17 highly sensitive to B. mori nucleopolyhedrovirus,Mol. Biotechnol., 40, 180-185 (2008).
119 Shin Kanamasa, Lies Dwiarti, Mitsuyasu Okabe and Enoch Y. Park, Cloning and Functional Characterization of the cis-Aconitic Acid Decarboxylase (CAD) Gene from Aspergillus terreus,Appl. Microbiol, Biotechnol.80, 223-229(2008).
118 Zhang-Nv Yang, Hai-Jun Xu, Enoch Y. Park, and Chuan-Xi Zhang, Characterization ofBombyx mori nucleopolyhedrovirus with a deletion of bm118Virus Research, 135, 220-229 (2008).
117 Tatsuya Kato, Ayano Kageshima, Fumiaki Suzuki, and Enoch Y. Park, Expression and purification of human (pro)renin receptor in insect cells using baculovirus expression system,Protein Expr. Purif., , 58, 242-248 (2008
116 Enoch Y. Park, Masayasu Sato, Seiji Kojima, Lipase-catalyzed biodiesel production from waste activated bleaching earth as raw material in pilot plant, Bioresource Technol., 99, 3130-3135 (2008)
115 Dongning Du, Tatsuya Kato, AHM Nurun Nabi, Fumiaki Suzuki, Enoch Y. Park, Expression of functional human (pro)renin receptor in silkworm larvae using BmNPV bacmid, Biotechnol. Appl. Biochem.,49(2), 195-202 (2008).
114 Enoch Y. Park, Takahiro Abe, and Tatsuya Kato, Improved expression of fusion protein using a cysteine protease and chitinase deficient Bombyx mori multiple nucleopolyhedrovirus bacmid in silkworm larvae,, Biotechnol. Appl. Biochem., 49(2), 135-140 (2008).<

2007

113 Tatsuya Kato and Enoch Y. Park, Specific expression of GFPuv-beta1,3-N-acetylglucosaminyltransferase 2 fusion protein in fat body of Bombyx mori silkworm larvae using signal peptide, Biochem. Biophys. Res. Commun., 359, 543-548 (2007).
112 Masato Hiyoshi, Ayano Kageshima, Tatsuya Kato, and Enoch Y. Park. Construction of cysteine protease deficient Bombyx mori nuclear polyhedrosis bacmid and its application on improved expression of fusion protein, J. Viol. Method, 144, 91-97 (2007).
111 Shin Kanamasa, Satoshi Tajima, Enoch Y. Park. Isocitrate dehydrogenase and isocitrate lyase of Ashbya gossypii are essential for its riboflavin production, Biotechnol. Biopress Eng.,12, 92-99 (2007).
110 Enoch Y. Park, Ayano Kageshima, Mi-Sun Kwon, and Tatsuya Kato. Enhanced production of secretory beta1,3-N-acetylglucosaminyltransferase 2 fusion protein into hemolymph of Bombyx mori larvae using recombinant BmNPV bacmid integrated signal sequence, J. Biotechnol., 129, 681-688 (2007).
109 Yuko Ikeda, Hiroyuki Hayashi, Naoyuki Okuda, and Enock Y. Park. Efficient Cellulase Production by the Filamentous Fungus Acremonium cellulolyticus, Biotechnol. Progress, 23, 333-8 (2007).
108 Enoch Y. Park, J. H. Zhang, S. Tajima, and L. Dwiarti, Isolation of Ashbya gossyoii mutant for an improved riboflavin production targeting for biorefinery technology, J. Appl. Microbiol.,103, 468-476 (2007).

2006

107 A. H. M. Nurun Nabi, Ayano Kageshima, Mohammad Nasir Uddin, Tsutomu Nakagawa, Enoch Y. Park, and Fumiaki Suzuki, Binding and enzymatic properties of recombinant rat (pro)renin receptor expressed in the baculovirus, Int’l J. Mol. Med. 18, 483-488 (2006)
106 Dongning Du, Masayasu Sato, Masahiro Mori, Enoch Y. Park, Repeated production of fatty acid methyl ester with activated bleaching earth in solvent-free system. Process Biochem. 41, 1849-1453 (2006).
105 Enoch Y. Park, Masayasu Sato, Seiji Kojima, Fatty acid methyl ester production using lipase-immobilizing silica particles with different particle sizes and different specific surface areas. Enz. Microb. Technol. 39, 889-896 (2006).
104 Kayo Koizumi, K. Higashiyama, Enoch Y. Park, Effects of amino acid on morphological development and nucleus formation of arachidonic acid-producing filamentous microorganism,Mortierella alpinaJ. Appl. Microbiol., 100, 885-892(2006).
103 V.K. Deo and Enoch Y. Park, Multiple cotransfection and coexpression of human b1,3-N-acetylglucosaminyltransferase with h-calreticulin chaperone cDNA in single step in insect cells.Biotechnol. Appl. Biochem., 43 (3), 129-135(2006).
102 V.K. Deo, M. Hiyoshi, A. Kageshima, Enoch Y Park, Construction of hybrid Autographa californica nuclear polyhedrosis bacmid by modification of p143 helicase. J. Viol. Method, 134, 212-216(2006)
101 Enoch Y. Park, K. Koizumi, and K. Higashiyam, Analysis of morphological diversity of Mortierella species using flow-through chamber coupled with image analysis, J. Eukaryot. Microbiol, 53(3), 199-203(2006)
100 u Bok Choi, Enoch Y. Park, Enhanced production of mouse a-amylase by feeding combined nitrogen and carbon sources in fed-batch cultureof recombinant Pichia pastorisProgress Biochemistry, 41, 390-397(2006)
99 T. Liu, S. Miura, M. Yaguchi, T. Arimura, Enock Y. Park, M. Okabe, Scale-up of L-lactic acid production by mutant strain Rhizopus sp. MK-96-1196 from 3-l to 5000-l in airlift bioreactors.J. Biosci. Bioeng., 101(1), 9-12 (2006).
98 Yuko Ikeda, Enoch Y Park, and Naoyuki Okuda, Bioconversion of waste office paper to gluconic acid in a turbine blade reactor by the filamentous fungus Aspergillus nigerBioresource Technol., 97, 1030-1035(2006).

2005

97 Enoch Y. Park and Masahiro Mori, Kinetic study of esterification of rapeseed oil contained in waste activated bleaching earth using Candida rugosa lipase in organic solvent system, J. Mol. Catal. B: Enz., 37, 95-100(2005)
96 T. Liu, S. Miura, T. Arimura, Enoch Y. Park, M-Y. Tei, and M. Okabe, High yield production of L-lactic acid with fed-batch culture in an airlift bioreactor by ammonia tolerant mutant strain Rhizopus sp. MK-96-1196, Biotechnol. and Bioprocess Eng., 10, 522-527(2005).
95. T. Miao, Y. Zhang, K. Nakagaki, T. Zhao, A. Zhao, Y. Meng, M. Nakagaki, Enoch Y. Park, and K. Maenaka, Expression of spider flagelliform silk protein in Bombyx mori cell line by a novel Bac-to-Bac/BmNPV baculovirus expression system. Appl. Microbiol. Biotechnol., 71, 192-199 (2006). doi.: 10.1007/s00253-005-0127-2
94 Tastuya Kato, Enoch Y. Park, Expression of alanine:glyoxylate aminotransferase gene from Saccharomyces cerevisiae in Ashbya gossypii Appl. Microbiol. Biotechnol. 71, 46-52 (2006).
93 Mami Suzuki, Testuya Kohsaka, and Enoch Y Park, Identification of epitope on DNA-binding protein expressed in insect cell infected by baculovirus, Mol. Biol. Rep, 33, 97-102 (2006)
92 Vipin Kumar Deo, Tatsuya Kato, Naoko Asari, and Enoch Y. Park, Quantitative screening of insect cell transformants stably expressing GFPuv-beta1,3-N-acetylglucosaminyltransferase 2 Fusion Protein, Biotechnol. Bioprocess Eng., 10, 275-279(2005).
91 Mi Sun Kwon, Tatsuya Kato, Takashi Dojima, and Enoch Y. Park, Application of radial-flow bioreactor on GFPuv-b1,3-N-acetylglucosaminyltransferase-2 fusion protein production using stably transformed insect cell lines, Biotechnol. Appl. Biochem., 42(1), 41-46(2005).
90 Tatsuya Kato, Mami Suzuki, Takeomi Murata, and Enoch Y. Park, The effects of N-glycosylation sites and the N-terminal region on the biological function of b1,3-N-acetylglucosaminyltransferase 2 and its secretion, Biochem. and Biophys. Res. Com., 329, 699-705 (2005).
89 Tatsuya Kato, Enoch Y Park, T. Murata, and T. Usui, Improvement of the production of production of GFPuv-beta1,3-N-acetylglucosaminyltransferase-2 fusion protein using insect cell-based expression system, Biotechnol. & Bioeng., 89(4), 424-433(2005).
88 Tomoko Motohashi, Tsukasa Shimojima, Tatsuro Fukagawa, Katsumi Maenaka and Enoch Y. Park, Efficient large-scale protein production of larvae and pupae of silkworm nuclear polyhedrosis virus (BmNPV) bacmid system, Biochem. and Biophys. Res. Com., 326, 564-569(2005).
87 Mi Sun Kwon, Takashi Dojima, and Enoch Y. Park,Use of plant-derived protein hydrolysate for enhancing growth of Bombyx mori insect cells, Biotechnol. Appl. Biochem., 41, 1-7 (2005).

2004

86 Enoch Y. Park and H. Ming, Oxidation of rapeseed oil in waste activated bleaching earth and its effect on riboflavin production in culture of Ashbya gossypii, J. Biosci. Bioeng., 97(1), 59-64 (2004).
85 Tatsuya Kato, Enoch Y Park,T. Murata, and T. Usui,Efficient production of human β1, 3-N-acetylglucosaminyltransferase-2 fused with green fluorescent protein in insect cell, Biochem. Eng. J, 19 (1), 15-23 (2004).
84 Tatsuya Kato, Enoch Y Park, T. Murata, and T. Usui,Comparative analysis of GFP β1,3-N-acetylglucosaminyltransferase 2 production in two insect-insect-cell-based expression systems,Protein Expression and Purification, 35 (1), 54-61(2004).
83 Enoch Y. Park, A. Kato and H. Ming, Riboflavin production using waste activated bleaching earth containing palm oil in the culture of Ashbya gossypii, J. Am. Oil Chem. Soc., 81(1), 57-62 (2004).
82 Vanessa Lara P., H. Ming, and Enoch Y. Park, Potential application of waste activated bleaching earth on the production of fatty acid alkyl ester using Candida cylyndracea lipase in organic solvent system,of fatty acid synthesis from Enzyme and Microbial Technol., 34(3/4), 270-277 (2004).
81 Enoch Y. Park, Pnam Ngoc Anh, and Naoyuki Okuda, Bioconversion of waste office paper to L(+)-lactic acid by filamentous microorganism Rhizopus oryzae, Bioresource Technol., 93(1), 77-83 (2004).
80 Seiji Kojima, D. Du, M. Sato., and Enoch Y Park: Efficient production of fatty acid methyl ester from waste activated bleaching earth using diesel oil as organic solvent, J. Biosci. Bioeng., 98 (6), 420-424 (2004). doi:10.1016/S1389-1723(05)00306-3

2003

79 S. H. Lim, H. Ming, Enoch Y. Park, and J. S. Choi, Improvement of riboflavin production using mineral support in the culture of Ashbya gossypii, Food Technol. Biotechnol., 41(2), 137-144 (2003).
78 Tatsuya Kato, Enoch Y Park, T. Murata, and T. Usui, Improvement of GFPuv-β3GnT2 fusion protein production by suppressing protease in baculovirus expression system, Biosci. Biotechnol. Biochem., 67(11),2388-2395 (2003).
77 M. S. Kwon, T. Dojima, and Enoch Y. Park, Comparative characteristics of growth and recombinant protein production in three insect cell lines with four serum free media, Biotechnol. Bioprocess Eng., 8, 142-146 (2003).
76 H. Ming, Ana V. Lara Pizarro, and Enoch Y. Park, Application of Waste Activated Bleaching Earth Containing Rapeseed Oil on Riboflavin Production in the Culture of Ashbya gossypii, Biotechnol. Prog., 19, 410-417 (2003).
75 V. Lara, Enoch Y. Park, Lipase-catalyzed production of biodiesel fuel from vegetable oils contained in waste activated bleaching earth, Process Biochem., 38, 1077-1082 (2003).

2002

74 Enoch Y. Park, Y. Ikeda, N. Okuda, Empirical evaluation of cellulase on enzymatic hydrolysis of waste office paper, Biotechnol. Bioprocess Eng., 7: 268-274 (2002).
73 T. Saito, T. Dojima, Enoch Y. Park, The effect of cell cycle on GFPuv gene expression in the baculovirus expression system, J. Biotechnol., 93: 121-129 (2002).
72 M. S. Kwon, T. Dojima, M. Toriyama, Enoch Y. Park, Development of an antibody-based assay for determination of baculovirus titers in 10 hours, Biotechnol. Prog. 18, 647-651 (2002).
71 Enoch Y. Park, T. Hamanaka, K. Higashiyama, S. Fujikawa, Monitoring of morphological development of the arachidonic-acid-producing filamentous microorganism Mortierella alpina, Appl. Microbiol. Biotechnol., 59: 706-712 (2002).
70 Kenichi Higashiyama, Shigeaki Fujikawa, Enoch Y. Park and Sakayu Shimizu, Production of arachidonic acid by Mortierella fungi, Biotechnol. Bioproc. Eng., 7, 252-262 (2002). doi.: 10.1007/BF02932833

2001

69 K. Prihardi, T. Iwata, J. Hiraki, Enoch Y. Park, M. Okabe, Enhancement of e-polysine production by Streptomyces albulus strain 410 using pH control, J. Biosci. Bioeng. 91 (2), 190-194 (2001).
68 T. Futamura, M. Okabe, T. Tamura, K. Toda, T. Matsunobu, Y. Park, Improvement of production of kojic acid by a mutant strain Aspergillus oryzae, MK107-39, J. Biosci. Bioeng., 91 (3), 272-276 (2001).
67 Y. Koike, H. J. Cai, K. Higashiyama, S. Fujikawa, Enoch Y. Park, Effect of consumed carbon to nitrogen source ratio on mycelial morphology and arachidonic acid production in culture of Motierella alpina, J. Biosci. Bioeng., 91(4), 382-389 (2001).
66 Enoch Y. Park, A. Michinaka, N. Okuda, Enzyme hydrolysis of waste office paper using viscosity as operating parameter, Biotechnol. Prog., 17, 379-382, (2001).
65 S. H. Lim, J. S. Choi, Enoch Y. Park, Microbial production of riboflavin using riboflavin overproducers, Ashbya gossypii, Bacillus subtilis, and Candida famate: an overview, Biotechnol. Bioprocess Eng., 6: 75-88 (2001).
64 Guowei Huang, M. Okabe, K. Prihardi, H. Tsunekawa, and Enoch Y. Park, Optimization of tylosin feeding rate profile in production of acetyl-isovaleryl tylosin (AIV) from tylosin by Streptomyces thermotolerans YN554, J. Biosc. Bioeng., 91(5), 504-508 (2001).
63 T. Hamanaka, K. Higashiyama, S. Fujikawa, and Enoch Y. Park, Mycelial pellet intrastructure and visualization of mycelia and intracellular lipid in a culture of Mortierella alpina, Appl. Microbiol. Biotechnol., 56: 233-238 (2001).
62 Enoch Y. Park, Yasuhisa Koike, Hong Jie Cai, Kenichi Higashiyama and Shigeaki Fujikawa, Morphological diversity of Mortierella alpina: Effect of consumed carbon to nitrogen ratio in flask culture, Biotechnol. Bioproc. Eng., 6: 161-166 (2001). doi.: 10.1007/BF02932544

Laboratory of Biotechnology.
Green Chemistry Research Division, Research Institute of Green Science and Technology